Charge-Tagged Acetate Ligands As Mass Spectrometry Probes for Metal Complexes Investigations: Applications in Suzuki and Heck Phosphine-Free Reactions

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• 作者：Felipe F. D. Oliveira ; Marcelo R. dos Santos ; Priscila M. Lalli ; Eduardo M. Schmidt ; Peter Bakuzis ; Alexandre A. M. Lapis ; Adriano L. Monteiro ; Marcos N. Eberlin ; Brenno A. D. Neto
• 刊名：Journal of Organic Chemistry
• 出版年：2011
• 出版时间：December 16, 2011
• 年：2011
• 卷：76
• 期：24
• 页码：10140-10147
• 全文大小：487K
• 年卷期：v.76,no.24(December 16, 2011)
• ISSN：1520-6904

文摘

An acetate anion bearing an imidazolium cation as its charge tag was reacted with M(OAc)₂ complexes (where M = Ni, Cu, and Pd; in situ reaction) to form members of a new class of charge-tagged metal complexes. The formation of these unprecedented precatalysts with potential for cross-coupling reactions was confirmed by electrospray ionization (and tandem) mass spectrometry. The catalytic performance of the palladium complex was tested in Heck and Suzuki cross-coupling reactions, often with superior activity and yields as compared with Pd(OAc)₂.