Rh-Catalyzed Asymmetric Hydrogenation of Cyclic 伪-Dehydroamino Ketones

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• 作者：Zhenfeng Zhang ; Qiupeng Hu ; Yingjie Wang ; Jianzhong Chen ; Wanbin Zhang
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：November 6, 2015
• 年：2015
• 卷：17
• 期：21
• 页码：5380-5383
• 全文大小：369K
• ISSN：1523-7052

文摘

Catalyzed by a rhodium complex of P-stereogenic diphosphine trichickenfootphos, five-membered cyclic 伪-dehydroamino ketones bearing endocyclic acyl and endocyclic vinyl groups were hydrogenated to give chiral 伪-amino ketones with quantitative conversions and excellent enantioselectivities.