Efficient Multigram Synthesis of the Repeating Unit of Gallic Acid-Triethylene Glycol Dendrimers
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- 作者：Sandra P. Amaral ; Marcos Fernandez-Villamarin ; Juan Correa ; Ricardo Riguera ; Eduardo Fernandez-Megia
- 刊名：Organic Letters
- 出版年：2011
- 出版时间：September 2, 2011
- 年：2011
- 卷：13
- 期：17
- 页码：4522-4525
- 全文大小：718K
- 年卷期：v.13,no.17(September 2, 2011)
- ISSN：1523-7052
文摘
A multigram synthesis of the repeating unit of GATG (gallic acid-triethylene glycol) dendrimers is described through an efficient and cost-effective route. These conditions overcome major problems precluding scaling up and afford product in excellent overall yield and purity. Special attention has been paid in this process to green chemistry principles: atom economy, safety, and waste reduction. This scheme could be easily adapted for the preparation of similar dendritic systems.