Cellular Level Biocompatibility and Biosafety of ZnO Nanowires

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• 作者：Zhou Li ; Rusen Yang ; Min Yu ; Fan Bai ; Cheng Li ; Zhong Lin Wang
• 刊名：Journal of Physical Chemistry C
• 出版年：2008
• 出版时间：December 25, 2008
• 年：2008
• 卷：112
• 期：51
• 页码：20114-20117
• 全文大小：228K
• 年卷期：v.112,no.51(December 25, 2008)
• ISSN：1932-7455

文摘

We report the first cellular level study on the biocompatibility and biosafety of ZnO nanowires (NWs). Hela cell line showed a complete biocompatibility to ZnO nanostructures from low to high NW concentrations beyond a couple of production periods. The L929 cell line showed a good reproduction behavior at lower NW concentration, but when the concentration was close to 100 μg/ml, the viability dropped to ∼50%. Our study shows the biocompetability and biosafety of ZnO NWs when they are applied in biological applications at normal concentration range.