A Latent Reaction in a Model GFP Chromophore Revealed upon Confinement: Photohydroxylation of ortho-Halo Benzylidene-3-methylimidazolidiones via an Electrocylization Process

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• 作者：Shampa R. Samanta ; Jos茅 P. Da Silva ; Anthony Baldridge ; Laren M. Tolbert ; V. Ramamurthy
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：June 20, 2014
• 年：2014
• 卷：16
• 期：12
• 页码：3304-3307
• 全文大小：287K
• 年卷期：v.16,no.12(June 20, 2014)
• ISSN：1523-7052

文摘

Excited state behavior of halogen substituted model GFP chromophores was investigated in an acetonitrile solution and in a confined environment provided by an octa acid capsule in water. Of the ortho, meta, and para halogen substituted GFP chromophores only the ortho compounds gave a new product resulting from an unprecedented photosubstitution of halogens by the hydroxyl group. This unusual reaction highlights the importance of confined spaces in bringing about some unattainable photoreactions.