Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)

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• 作者：Zenaida Mendoza ; Pablo Lorenzo-Luis ; Manuel Serrano-Ruiz ; Elva Martín-Batista ; José M. Padrón ; Franco Scalambra ; Antonio Romerosa
• 刊名：Inorganic Chemistry
• 出版年：2016
• 出版时间：August 15, 2016
• 年：2016
• 卷：55
• 期：16
• 页码：7820-7822
• 全文大小：253K
• 年卷期：0
• ISSN：1520-510X

文摘

The complex [RuCp(PPh₃)₂(HdmoPTA)](OSO₂CF₃)₂ (2; HdmoPTA = 3,7-H-3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane) was synthesized and characterized. Its crystal structure was determined by single-crystal X-ray diffraction. The complex showed a more potent antiproliferative activity than cisplatin against a representative panel of human cancer cells.