Iron/Zinc-Co-catalyzed Directed Arylation and Alkenylation of C(sp3)–H Bonds with Organoborates

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• 作者：Laurean Ilies ; Yuki Itabashi ; Rui Shang ; Eiichi Nakamura
• 刊名：ACS Catalysis
• 出版年：2017
• 出版时间：January 6, 2017
• 年：2017
• 卷：7
• 期：1
• 页码：89-92
• 全文大小：337K
• ISSN：2155-5435

文摘

An iron(III) salt, (Z)-1,2-bis(diphenylphosphino)ethene or its electron-rich congener, (Z)-1,2-bis[bis(4-methoxyphenyl)phosphine]ethene, and a zinc(II) salt catalyze the arylation, heteroarylation, and alkenylation of propionamides possessing an 8-quinolylamide group with organoborate reagents in the presence of 1,2-dichlorobutane as oxidant at 70 °C. Stoichiometric experiments provided evidence for the involvement of an organoiron(III) species as a key intermediate for C–H activation and C–C bond formation.