Metabolites of Antroquinonol Found in Rat Urine Following Oral Administration
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- 作者：Chien-Kuang Chen ; Jaw-Jou Kang ; Wu-Che Wen ; Hui-Fen Chiang ; Shoei-Sheng Lee
- 刊名：Journal of Natural Products
- 出版年：2014
- 出版时间：April 25, 2014
- 年：2014
- 卷：77
- 期：4
- 页码：1061-1064
- 全文大小：207K
- 年卷期：v.77,no.4(April 25, 2014)
- ISSN：1520-6025
文摘
Four metabolites (1鈥?b>4) of antroquinonol from rat urine, collected within 24 h after oral administration of antroquinonol, were characterized by HPLC鈥揝PE鈥揘MR. Compounds 1鈥?b>4 were further isolated by semipreparative HPLC for structure confirmation. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopic analyses and HRESIMS data.