Chemical Constituents from the Fruiting Bodies of Hexagonia apiaria and Their Anti-inflammatory Activity
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- 作者：Tran Dinh Thang ; Ping-Chung Kuo ; Nguyen Thi Bich Ngoc ; Tsong-Long Hwang ; Mei-Lin Yang ; Shih-Huang Ta ; E-Jian Lee ; Dai-Huang Kuo ; Nguyen Huy Hung ; Nguyen Ngoc Tuan ; Tian-Shung Wu
- 刊名：Journal of Natural Products
- 出版年：2015
- 出版时间：November 25, 2015
- 年：2015
- 卷：78
- 期：11
- 页码：2552-2558
- 全文大小：297K
- ISSN：1520-6025
文摘
A chemical investigation of the fruiting bodies of Hexagonia apiaria resulted in the identification of nine compounds including five new triterpenoids, hexagonins A鈥揈 (1鈥?b>5), along with four known compounds. The purified constituents were examined for their anti-inflammatory activity. Among the tested compounds, hexatenuin A displayed the most significant inhibition of superoxide anion generation and elastase release. These triterpenoids may have potentials as anti-inflammatory agents.