Rhodium-Catalyzed Asymmetric Cyclodimerization of Oxa- and Azabicyclic Alkenes
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- 作者：Takahiro Nishimura ; Takahiro Kawamoto ; Keigo Sasaki ; Eiji Tsurumaki ; Tamio Hayashi
- 刊名：Journal of the American Chemical Society
- 出版年：2007
- 出版时间：February 14, 2007
- 年：2007
- 卷：129
- 期：6
- 页码：1492 - 1493
- 全文大小：66K
- 年卷期：v.129,no.6(February 14, 2007)
- ISSN：1520-5126
文摘
Asymmetric homo-cyclodimerization of oxabicyclic alkenes proceeded with high efficiency in the presence of a cationic rhodium/(R)-binap catalyst to give high yields of chiral tetrahydrofurans of up to 99% ee. The cationic rhodium complex also catalyzed the asymmetric cross-cyclodimerization between oxabicyclic alkenes and dimethyl 2-butynedioate, which gave dihydrofurans as [3 + 2] cycloadducts with high enantioselectivity (99% ee).