Silver-Catalyzed Radical Tandem Cyclization for the Synthesis of 3,4-Disubstituted Dihydroquinolin-2(1H)-ones

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• 作者：Wen-Peng Mai ; Ji-Tao Wang ; Liang-Ru Yang ; Jin-Wei Yuan ; Yong-Mei Xiao ; Pu Mao ; Ling-Bo Qu
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：January 3, 2014
• 年：2014
• 卷：16
• 期：1
• 页码：204-207
• 全文大小：321K
• ISSN：1523-7052

文摘

A silver-catalyzed tandem decarboxylative radical addition/cyclization of N-arylcinnamamides with aliphatic carboxylic acids is reported. This method affords a novel and straightforward route to various 3,4-disubstituted dihydroquinolin-2(1H)-ones in aqueous solution.