Development and Application of a Multielectron-Accepting Organic Oxidant for the Catalytic Transition-Metal-Free Oxidative Homocoupling of Grignard Reagents in Air
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- 作者：Toshinobu Korenaga ; Kaoru Nitatori ; Hiroki Muraoka ; Satoshi Ogawa ; Kazuaki Shimada
- 刊名：Organic Letters
- 出版年：2015
- 出版时间：November 6, 2015
- 年：2015
- 卷：17
- 期：21
- 页码：5500-5503
- 全文大小：333K
- ISSN：1523-7052
文摘
Heptafluorotolyl-substituted perfluorocyclopentene acts as a four-electron oxidant for the homocoupling of Grignard reagents. It can also be used for catalytic homocoupling with a low catalyst loading (up to 2 mol %) in the presence of atmospheric oxygen. The organocatalytic cycle involves the generation of an organic radical and a perfluorocyclopentadienyl anion.