Effects of Whey Protein Concentrate (WPC) on the Distributions of Lymphocyte Subpopulations in Rats with Excessive Alcohol Intake
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- 作者：Yang-Ming Tseng ; Shih-Meng Tsai ; Wen-Shan Lin ; Zih-Ru Huang ; Chun-Chin Lin ; Wei-Hao Yeh ; Yi-Ru Wu ; Li-Yu Tsai
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2010
- 出版时间：December 22, 2010
- 年：2010
- 卷：58
- 期：24
- 页码：12729-12734
- 全文大小：712K
- 年卷期：v.58,no.24(December 22, 2010)
- ISSN：1520-5118
文摘
To investigate the effects of whey protein concentrate (WPC) on antioxidant statuses and the lymphocyte subpopulations in the rats with alcohol intake, the antioxidant statuses in the peripheral blood (PB) and the lymphocyte subpopulations in the PB, spleen, and bone marrow (BM) of the rats fed with WPC (0.334 g/kg) and alcohol (6 g/kg) for 3 months were analyzed. Results showed that the effects of WPC on the glutathione peroxidase and glutathione in the PB, the T and B cells in the spleen, and the B cells in the BM were more apparent in the rats with alcohol intake; however, they are not apparent in the controls. Taken together, our results indicated that the immunity of rats might be enhanced by the increased antioxidant ability after WPC supplementation and the effects of WPC on the lymphocyte subpopulations were mainly in the spleen and BM and not in the PB.