Development of Magnetic Nanostructured Silica-Based Materials as Potential Vectors for Drug-Delivery Applications

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• 作者：Manuel Arruebo ; Marta Galá ; n ; Nuria Navascué ; s ; Carlos Té ; llez ; Clara Marquina ; M. Ricardo Ibarra ; and Jes&uacute ; s Santamarí ; a
• 刊名：Chemistry of Materials
• 出版年：2006
• 出版时间：April 4, 2006
• 年：2006
• 卷：18
• 期：7
• 页码：1911 - 1919
• 全文大小：817K
• 年卷期：v.18,no.7(April 4, 2006)
• ISSN：1520-5002

文摘

Metallic iron nanoparticles were synthesized within micron-sized mesoporous molecular sieves (with2.9-nm pores) and hollow silica microcapsules (pores of 2.7 and 15 nm) using several cycles of wetimpregnation under vacuum, followed by drying, oxidation, and reduction steps. For iron-loaded MCM-48, SQUID measurements revealed ferromagnetic behavior at room temperature with a magnetic momentas high as 3.40 emu/g (measured at 2 T) after four deposition cycles. Iron-loaded hollow silicamicrocapsules (250-nm wall thickness) showed a magnetic moment of 2.40 emu/g (at 2 T) after threedeposition cycles and a coercivity as low as 12.9 Oe.