Nanoclustered Gold Honeycombs for Surface-Enhanced Raman Scattering

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• 作者：Weinan Leng ; Peter J. Vikesland
• 刊名：Analytical Chemistry
• 出版年：2013
• 出版时间：February 5, 2013
• 年：2013
• 卷：85
• 期：3
• 页码：1342-1349
• 全文大小：441K
• 年卷期：v.85,no.3(February 5, 2013)
• ISSN：1520-6882

文摘

A honeycomb-shaped gold substrate was developed for surface-enhanced Raman imaging (SERI). The honeycombs are composed of clusters of 50鈥?0 nm gold nanoparticles and exhibit high Raman enhancement efficiency. An average surface enhancement factor (ASEF) of 1.7 脳 10⁶ was estimated for a monolayer of l-cysteine molecules adsorbed to gold via a thiol linkage. The presence of a linear relationship in the low concentration region was observed in SERI detection of malachite green isothiocyanate (MGITC). These results together with the high reproducibility and simple and cost-effective fabrication of this substrate suggest that it has utility for applications of surface-enhanced Raman scattering (SERS) in quantitative diagnoses and analyte detection.