Fluorescent N-Doped Carbon Dots as in Vitro and in Vivo Nanothermometer

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• 作者：Yanmei Yang ; Weiqian Kong ; Hao Li ; Juan Liu ; Manman Yang ; Hui Huang ; Yang Liu ; Zhongyang Wang ; Zhiqiang Wang ; Tsun-Kong Sham ; Jun Zhong ; Chao Wang ; Zhuang Liu ; Shuit-Tong Lee ; Zhenhui Kang
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2015
• 出版时间：December 16, 2015
• 年：2015
• 卷：7
• 期：49
• 页码：27324-27330
• 全文大小：506K
• ISSN：1944-8252

文摘

The fluorescent N-doped carbon dots (N-CDs) obtained from C₃N₄ emit strong blue fluorescence, which is stable with different ionic strengths and time. The fluorescence intensity of N-CDs decreases with the temperature increasing, while it can recover to the initial one with the temperature decreasing. It is an accurate linear response of fluorescence intensity to temperature, which may be attributed to the synergistic effect of abundant oxygen-containing functional groups and hydrogen bonds. Further experiments also demonstrate that N-CDs can serve as effective in vitro and in vivo fluorescence-based nanothermometer.