Applications of Metabolomics in Agriculture

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• 作者：Richard A. Dixon ; David R. Gang ; Adrian J. Charlton ; Oliver Fiehn ; Harry A. Kuiper ; Tracey L. Reynolds ; Ronald S. Tjeerdema ; Elizabeth H. Jeffery ; J. Bruce German ; William P. Ridley ; James N. Seiber
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2006
• 出版时间：November 29, 2006
• 年：2006
• 卷：54
• 期：24
• 页码：8984 - 8994
• 全文大小：191K
• 年卷期：v.54,no.24(November 29, 2006)
• ISSN：1520-5118

文摘

Biological systems are exceedingly complex. The unraveling of the genome in plants and humansrevealed fewer than the anticipated number of genes. Therefore, other processes such as theregulation of gene expression, the action of gene products, and the metabolic networks resultingfrom catalytic proteins must make fundamental contributions to the remarkable diversity inherent inliving systems. Metabolomics is a relatively new approach aimed at improved understanding of thesemetabolic networks and the subsequent biochemical composition of plants and other biologicalorganisms. Analytical tools within metabolomics including mass spectrometry (MS) and nuclearmagnetic resonance (NMR) spectroscopy can profile the impact of time, stress, nutritional status,and environmental perturbation on hundreds of metabolites simultaneously resulting in massive,complex data sets. This information, in combination with transcriptomics and proteomics, has thepotential to generate a more complete picture of the composition of food and feed products, to optimizecrop trait development, and to enhance diet and health. Selected presentations from an AmericanChemical Society symposium held in March 2005 have been assembled to highlight the emergingapplication of metabolomics in agriculture.