Caffeoyl Triterpenes from Pear (Pyrus pyrifolia Nakai) Fruit Peels and Their Antioxidative Activities against Oxidation of Rat Blood Plasma
详细信息 查看全文
- 作者：Jeong-Yong Cho ; Chan Mi Kim ; Hyoung Jae Lee ; Sang-Hyun Lee ; Jeong-An Cho ; Wol-Soo Kim ; Keun-Hyung Park ; Jae-Hak Moon
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2013
- 出版时间：May 15, 2013
- 年：2013
- 卷：61
- 期：19
- 页码：4563-4569
- 全文大小：289K
- 年卷期：v.61,no.19(May 15, 2013)
- ISSN：1520-5118
文摘
Six triterpenes, including three caffeoyl triterpenes, were purified and isolated from pear fruit (Pyrus pyrifolia Nakai cv. Chuwhangbae) peel extracts using various column chromatography techniques with a guided 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay. The isolated compounds were identified as betulinic aldehyde (1), lupeol (2), betulinic acid (3), 3-O-cis-caffeoylbetulinic acid (4), 3-O-trans-caffeoylbetulinic acid (5), and 3-O-trans-caffeoyloleanolic acid (6) on the basis of nuclear magnetic resonance spectroscopy and electrospray ionization mass spectrometry. Four compounds (1, 4鈥?b>6) were identified from Asian pear fruit for the first time. In addition, compounds 4鈥?b>6, containing a caffeic acid moiety, showed higher DPPH radical-scavenging and suppression effects against copper ion-induced oxidation of rat blood plasma than other compounds without a caffeic acid moiety.