Toxicity of Bisabolangelone from Ostericum koreanum Roots to Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae)

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• 作者：Suk-Woo Kang ; Hyun-Kyung Kim ; Won-Ja Lee ; and Young-Joon Ahn
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2006
• 出版时间：May 17, 2006
• 年：2006
• 卷：54
• 期：10
• 页码：3547 - 3550
• 全文大小：46K
• 年卷期：v.54,no.10(May 17, 2006)
• ISSN：1520-5118

文摘

The acaricidal activity of materials derived from the roots of Ostericum koreanum (Apiaceae) towardadults of Dermatophagoides farinae and Dermatophagoides pteronyssinus was examined by directcontact and vapor phase toxicity bioassays. Results were compared with those of three acaricides:benzyl benzoate, dibutyl phthalate, and N,N-diethyl-m-toluamide (DEET). The active principle wasidentified as the sesquiterpenoid bisabolangelone by spectroscopic analysis. In fabric-piece contacttoxicity bioassays using adult D. farinae, bisabolangelone (1.88 gif">g/cm²) was more toxic than benzylbenzoate (11.91 gif">g/cm²), DEET (62.20 gif">g/cm²), or dibutyl phthalate (79.54 gif">g/cm²), based on 24-hLD₅₀ values. Against adult D. pteronyssinus, bisabolangelone (1.79 gif">g/cm²) was similarly more activethan benzyl benzoate (9.65 gif">g/cm²), DEET (64.45 gif">g/cm²), and dibutyl phthalate (77.79 gif">g/cm²). Invapor phase toxicity tests with both mite species, bisabolangelone was equitoxic in closed versusopen containers. These results indicate that bisabolangelone was largely toxic through contact action.Bisabolangelone merits further study as a potential contact acaricide or lead for the control of housedust mites.Keywords: Ostericum koreanum; Apiaceae; botanical acaricide; house dust mite; Dermatophagoidesfarinae; Dermatophagoides pteronyssinus; contact action; bisabolangelone