Psiguadials A and B, Two Novel Meroterpenoids with Unusual Skeletons from the Leaves of Psidium guajava
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- 作者：Meng Shao ; Ying Wang ; Zhong Liu ; Dong-Mei Zhang ; Hui-Hui Cao ; Ren-Wang Jiang ; Chun-Lin Fan ; Xiao-Qi Zhang ; He-Ru Chen ; Xin-Sheng Yao ; Wen-Cai Ye
- 刊名：Organic Letters
- 出版年：2010
- 出版时间：November 5, 2010
- 年：2010
- 卷：12
- 期：21
- 页码：5040-5043
- 全文大小：202K
- 年卷期：v.12,no.21(November 5, 2010)
- ISSN：1523-7052
文摘
Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.