I2-Catalyzed Synthesis of Substituted Pyrroles from α-Amino Carbonyl Compounds and Aldehydes

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• 作者：Rulong Yan ; Xing Kang ; Xiaoqiang Zhou ; Xiaoni Li ; Xingxing Liu ; Likui Xiang ; Yamin Li ; Guosheng Huang
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：January 3, 2014
• 年：2014
• 卷：79
• 期：1
• 页码：465-470
• 全文大小：256K
• ISSN：1520-6904

文摘

A direct method for the synthesis of 1,3,4-triarylpyrroles was achieved easily from cyclization of 伪-amino carbonyl compounds and aldehydes catalyzed by I₂. Various substituted groups can be employed, and this reaction can proceed smoothly in moderate to good yields.