Spin-Casting Polymer Brush Films for Stimuli-Responsive and Anti-Fouling Surfaces

详细信息    查看全文

• 作者：Binbin Xu ; Chun Feng ; Jianhua Hu ; Ping Shi ; Guangxin Gu ; Lei Wang ; Xiaoyu Huang
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2016
• 出版时间：March 16, 2016
• 年：2016
• 卷：8
• 期：10
• 页码：6685-6692
• 全文大小：457K
• ISSN：1944-8252

文摘

Surfaces modified with amphiphilic polymers can dynamically alter their physicochemical properties in response to changes of their environmental conditions; meanwhile, amphiphilic polymer coatings with molecular hydrophilic and hydrophobic patches, which can mitigate biofouling effectively, are being actively explored as advanced coatings for antifouling materials. Herein, a series of well-defined amphiphilic asymmetric polymer brushes containing hetero side chains, hydrophobic polystyrene (PS) and hydrophilic poly(ethylene glycol) (PEG), was employed to prepare uniform thin films by spin-casting. The properties of these films were investigated by water contact angle, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), and quartz crystal microbalance (QCM). AFM showed smooth surfaces for all films with the roughness less than 2 nm. The changes in water contact angle and C/O ratio (XPS) evidenced the enrichment of PEG or PS chains at film surface after exposed to selective solvents, indicative of stimuli- responsiveness. The adsorption of proteins on PEG functionalized surface was quantified by QCM and the results verified that amphiphilic polymer brush films bearing PEG chains could lower or eliminate protein-material interactions and resist to protein adsorption. Cell adhesion experiments were performed by using HaCaT cells and it was found that polymer brush films possess good antifouling ability.