Naphthalenones from a Perenniporia sp. Inhabiting the Larva of a Phytophagous Weevil, Euops chinesis

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• 作者：Yu Feng ; Lin Wang ; Shubin Niu ; Li Li ; Yikang Si ; Xingzhong Liu ; Yongsheng Che
• 刊名：Journal of Natural Products
• 出版年：2012
• 出版时间：July 27, 2012
• 年：2012
• 卷：75
• 期：7
• 页码：1339-1345
• 全文大小：386K
• 年卷期：v.75,no.7(July 27, 2012)
• ISSN：1520-6025

文摘

The new naphthalenone derivatives perenniporides A鈥揇 (1鈥?b>4) were isolated from solid cultures of a fungus Perenniporia sp. inhabiting the larva of Euops chinesis, a phytophagous weevil with high host specificity to the medicinal plant Fallopia japonica. The structures of 1鈥?b>4 were elucidated primarily by NMR experiments, and 1 was confirmed by X-ray crystallography. The absolute configuration of 1 and 2 was assigned by electronic circular dichroism (ECD) calculations, whereas that of the C-10 tertiary alcohol in 3 was deduced via the CD data of the in situ formed [Rh₂(OCOCF₃)₄] complex and supported by the ECD data. Compound 1 showed antifungal activity against five plant pathogens.