Gold-Catalyzed Direct Assembly of Aryl-Annulated Carbazoles from 2-Alkynyl Arylazides and Alkynes

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• 作者：Nan Li ; Xiao-Lei Lian ; Yu-Hui Li ; Tian-Yi Wang ; Zhi-Yong Han ; Liming Zhang ; Liu-Zhu Gong
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：September 2, 2016
• 年：2016
• 卷：18
• 期：17
• 页码：4178-4181
• 全文大小：404K
• 年卷期：0
• ISSN：1523-7052

文摘

An unprecedented gold-catalyzed synthetic method for the direct assembly of aryl-annulated carbazoles from 2-alkynyl arylazides and alkynes is described. The reaction is proposed to proceed via a sequential cyclopropenation and intramolecular metal carbene/arene Friedel–Crafts-type reaction, respectively, mediated by two gold carbene intermediates.