Palladium-Catalyzed Acylation/Alkenylation of Aryl Iodide: A Domino Approach Based on the Catellani鈥揕autens Reaction
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- 作者：Ping-Xin Zhou ; Yu-Ying Ye ; Ce Liu ; Lian-Biao Zhao ; Jian-Ye Hou ; Dao-Qian Chen ; Qian Tang ; An-Qi Wang ; Jie-Yu Zhang ; Qi-Xing Huang ; Peng-Fei Xu ; Yong-Min Liang
- 刊名：ACS Catalysis
- 出版年：2015
- 出版时间：August 7, 2015
- 年：2015
- 卷：5
- 期：8
- 页码：4927-4931
- 全文大小：410K
- ISSN：2155-5435
文摘
A new palladium-catalyzed three-component coupling involving acylation/alkenylation of aryl iodide is reported. The reaction was carried out with readily available starting materials and gave the ortho-acylated styrene in moderate to good yields. Compared with previous Catellani鈥揕autens reactions, this reaction is the first example of introducing an acyl group at the ortho position of aryl iodides. The proposed PdIV complex, generated via oxidative addition of the carboxylic anhydrides, is a key intermediate for this transformation.