Studies of Ionic Current Rectification Using Polyethyleneimines Coated Glass Nanopipettes
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- 作者：Shujuan Liu ; Yitong Dong ; Wenbo Zhao ; Xiang Xie ; Tianrong Ji ; Xiaohong Yin ; Yun Liu ; Zhongwei Liang ; Dmitry Momotenko ; Dehai Liang ; Hubert H. Girault ; Yuanhua Shao
- 刊名：Analytical Chemistry
- 出版年：2012
- 出版时间：July 3, 2012
- 年：2012
- 卷：84
- 期：13
- 页码：5565-5573
- 全文大小：381K
- 年卷期：v.84,no.13(July 3, 2012)
- ISSN：1520-6882
文摘
The modification of glass nanopipettes with polyethyleneimines (PEIs) has been successfully achieved by a relatively simple method, and the smallest tip opening is around 3 nm. Thus, in a much wider range of glass pipettes with radii from several nanometers to a few micrometers, the ion current rectification (ICR) phenomenon has been observed. The influences of different KCl concentrations, pH values, and tip radii on the ICR are investigated in detail. The sizes of PEIs have been determined by dynamic light scattering, and the effect of the sizes of PEIs for the modification, especially for a few nanometer-pipettes in radii, is also discussed. These findings systemically confirm and complement the theoretical model(7, 18) and provide a platform for possible selectively molecular detection and mimic biological ion channels.