CuO-Promoted Construction of N-2-Aryl-Substituted-1,2,3-Triazoles via Azide-Chalcone Oxidative Cycloaddition and Post-Triazole Arylation
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- 作者：Yuanqing Zhang ; Xiaolong Li ; Jihui Li ; Jinying Chen ; Xu Meng ; Mingming Zhao ; Baohua Chen
- 刊名：Organic Letters
- 出版年：2012
- 出版时间：January 6, 2012
- 年：2012
- 卷：14
- 期：1
- 页码：26-29
- 全文大小：695K
- 年卷期：v.14,no.1(January 6, 2012)
- ISSN：1523-7052
文摘
An efficient one-pot three-component stepwise approach for the synthesis of N-2-aryl-substituted-1,2,3-triazoles has been developed. By using this azide-chalcone oxidative cycloaddition and post-triazole arylation, a series of N-2-aryl-substituted-1,2,3-triazoles are readily prepared under mild conditions in excellent yields and high regioselectivity. Both the catalyst and substrates are readily available.