Development and Validation of a Method for the Determination of 159 Pesticide Residues in Tobacco by Gas Chromatography鈥揟andem Mass Spectrometry
详细信息 查看全文
- 作者：Xiaoshui Chen ; Zhaoyang Bian ; Hongwei Hou ; Fei Yang ; Shanshan Liu ; Gangling Tang ; Qingyuan Hu
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2013
- 出版时间：June 19, 2013
- 年：2013
- 卷：61
- 期：24
- 页码：5746-5757
- 全文大小：247K
- 年卷期：v.61,no.24(June 19, 2013)
- ISSN：1520-5118
文摘
A multiresidue gas chromatography鈥搕andem mass spectrometry (GC-MS/MS) method was developed for the analysis of 159 multiclass pesticides in tobacco. A modified QuEChERS sample preparation technique, based on acetonitrile extraction and toluene dilution, followed by dispersive solid-phase extraction (d-SPE) cleanup using primary鈥搒econdary amine (PSA) and octadecyl (C18) sorbents, was used for sample treatment. Key performance parameters investigated were linearity, recovery, relative standard deviation (RSD), limit of detection, and limit of quantitation. With the exception of chinomethionate and folpet, recoveries for pesticides ranged from 69 to 141%, and the RSDs ranged from 2 to 27%. The validated method was applied to the analysis of 118 real samples, and positive results were obtained for 116 samples, with 25 different pesticides being detected.