Palladium-Catalyzed/Norbornene-Mediated ortho-Amination/N-Tosylhydrazone Insertion Reaction: An Approach to the Synthesis of ortho-Aminated Vinylarenes
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- 作者：Ping-Xin Zhou ; Yu-Ying Ye ; Jun-Wei Ma ; Lan Zheng ; Qian Tang ; Yi-Feng Qiu ; Bo Song ; Zi-Hang Qiu ; Peng-Fei Xu ; Yong-Min Liang
- 刊名：Journal of Organic Chemistry
- 出版年：2014
- 出版时间：July 18, 2014
- 年：2014
- 卷：79
- 期：14
- 页码：6627-6633
- 全文大小：381K
- ISSN：1520-6904
文摘
ortho-Aminated vinylarene derivatives were obtained via a reaction of aryl iodides, N-benzoyloxyamines, and N-tosylhydrazones. This approach involves a palladium-catalyzed, norbornene-mediated ortho-amination/N-tosylhydrazone insertion reaction. In this transformation, one C鈥揘 bond and one C鈥揅 bond are formed and an amine group is introduced at the ortho position successfully.