Thermal Diffusion of Nucleotides

详细信息    查看全文

• 作者：Zilin Wang ; Hartmut Kriegs ; Simone Wiegand
• 刊名：The Journal of Physical Chemistry B
• 出版年：2012
• 出版时间：June 28, 2012
• 年：2012
• 卷：116
• 期：25
• 页码：7463-7469
• 全文大小：446K
• 年卷期：v.116,no.25(June 28, 2012)
• ISSN：1520-5207

文摘

We investigate the thermal diffusion behavior of aqueous solutions of nucleotides using an infrared thermal diffusion forced Rayleigh scattering (IR-TDFRS) setup. In this work we study 5 nucleotides: cyclic nucleotides adenosine and guanosine monophosphate, 5鈥?adenosine and 5鈥?cytidine monophosphate, and also adenosine diphosphate in water. The structures of nucleotides vary systematically, which results in different physical properties such as acidity, solubility, hydrophobicity, and melting point. We discuss the connection between the thermal diffusion behavior and the properties of the different nucleotides. Additionally, as in the case of the alkanes and monoscaccharides, we find a correlation between the thermal diffusion coefficient and the ratio of the thermal expansion coefficient and the kinematic viscosity.