A Minor Diterpenoid with a New 6/5/7/3 Fused-Ring Skeleton from Euphorbia micractina

详细信息    查看全文

• 作者：Ye Tian ; Qinglan Guo ; Wendong Xu ; Chenggen Zhu ; Yongchun Yang ; Jiangong Shi
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：August 1, 2014
• 年：2014
• 卷：16
• 期：15
• 页码：3950-3953
• 全文大小：251K
• ISSN：1523-7052

文摘

A novel diterpenoid with an unprecedented 6/5/7/3 fused-ring skeleton, euphorbactin (1), was isolated from an ethanol extract of the roots of Euphorbia micractina. The structure was determined by extensive spectroscopic studies, especially by 2D NMR and CD data analysis. A proposed biosynthetic pathway and preliminary investigations of the biological activity of compound 1 are also discussed.