pH- and Glucose-Responsive Core鈥揝hell Hybrid Nanoparticles with Controllable Metal-Enhanced Fluorescence Effects
详细信息 查看全文
- 作者：Jianfeng Zhang ; Ning Ma ; Fu Tang ; Qianling Cui ; Fang He ; Lidong Li
- 刊名：ACS Applied Materials & Interfaces
- 出版年：2012
- 出版时间：March 28, 2012
- 年：2012
- 卷：4
- 期：3
- 页码：1747-1751
- 全文大小：249K
- 年卷期：v.4,no.3(March 28, 2012)
- ISSN：1944-8252
文摘
In this paper, a novel core鈥搒hell hybrid nanoparticle with a silver core and cross-linked poly(3-acrylamidephenylboronic acid-co-acrylic acid) shell (Ag@PAPBA-PAA) was reported. The prepared hybrid nanoparticles can exhibit good responsiveness to the glucose concentration and pH of the environment and exhibit a responsive swelling and shrinking behavior. Tuned by the glucose concentration or pH, a swelling of up to 15.0 nm thickness of the hybrid nanoparticle shell can be observed. These unique responsive properties can be employed to tune the metal-enhanced fluorescence (MEF) effects of the incorporated Ag cores. The fluorescence of adsorbed positively charged porphyrin molecules (Por4+) shows good sensitivity to the glucose concentration and pH with an enhancement of up to about 1.8-fold. These functional hybrid nanoparticles with tunable MEF effects show a great potential application in the fields of responsive fluorescent sensing and detection.