α-Amidino Rhodium Carbenes: Key Intermediates for the Preparation of (E)-2-Aminomethylene-3-oxoindoles and Pyranoindoles

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• 作者：Jing Qian ; Guorong Sheng ; Kai Huang ; Shaojie Liu ; Ping Lu ; Yanguang Wang
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：August 5, 2016
• 年：2016
• 卷：18
• 期：15
• 页码：3682-3685
• 全文大小：340K
• 年卷期：0
• ISSN：1523-7052

文摘

Rhodium-catalyzed reactions of 3-diazoindolin-2-imines with aromatic aldehydes and α,β-unsaturated aldehydes respectively furnished (E)-2-aminomethylene-3-oxoindoles and pyranoindoles in moderate to excellent yields with nice functional group tolerance. The reaction proceeds in a cascade involving α-amidino rhodium carbene as the key intermediate.