The N-Aryl Aminocarbonyl ortho-Substituent Effect in Cu-Catalyzed Aryl Amination and Its Application in the Synthesis of 5-Substituted 11-Oxo-dibenzodiazepines

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• 作者：Xiaoqiong Diao ; Lanting Xu ; Wei Zhu ; Yongwen Jiang ; Haoyang Wang ; Yinlong Guo ; Dawei Ma
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：December 16, 2011
• 年：2011
• 卷：13
• 期：24
• 页码：6422-6425
• 全文大小：756K
• 年卷期：v.13,no.24(December 16, 2011)
• ISSN：1523-7052

文摘

Double amination of ortho-substituted aryl bromides proceeded under mild conditions to afford 5-substituted 11-oxo-dibenzodiazepines, which revealed that there is a strong ortho-substituent effect caused by N-aryl aminocarbonyl groups during copper-catalyzed aryl amination.