Radionuclides used for therapy and suggestion for new candidates

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• 作者：M. Neves ; A. Kling and A. Oliveira
• 刊名：Journal of Radioanalytical and Nuclear Chemistry
• 出版年：2005
• 出版时间：November 2005
• 年：2005
• 卷：266
• 期：3
• 页码：377-384
• 全文大小：82 KB

文摘

Targeted radiotherapy has the potential to provide radiation doses from a wide range of radionuclides, some of them suitable for killing single cells while others are more suitable for killing tumor cell clusters of various sizes. A list of 64 radionuclides, including 20 new potential candidates for therapy (73Ga, 75Se, 87mSr, 97Ru, 103Ru, 113Sn, 113mIn, 117Sb, 123Sn, 131Cs, 139Ce, 141Ce, 149Eu, 167Tm, 170Tm, 173Tm, 195Au, 195mPt, 197Pt and 197Hg) were analyzed in terms of the suitability of their energies for killing tumor cells which grow as single, small, intermediate and large clusters. In addition, their possible production routes were studied.