miR-324-3p suppresses migration and invasion by targeting WNT2B in nasopharyngeal carcinoma

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• 作者：Chao Liu ; Guo Li ; Nianting Yang ; Zhongwu Su ; Shuiting Zhang…
• 关键词：Nasopharyngeal carcinoma ; miR ; 324 ; 3p ; WNT2B ; Invasion
• 刊名：Cancer Cell International
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：3005KB
• 刊物主题：Cancer Research; Cell Biology;
• 出版者：BioMed Central
• ISSN：1475-2867
• 卷排序：17

文摘

BackgroundNasopharyngeal carcinoma (NPC) is a malignant epithelial carcinoma of the head and neck with strong ability of invasion and metastasis. Our previous study indicated that miR-324-3p, as a tumor-suppressive factor, could regulate radioresistance of NPC cells by targeting WNT2B. The purpose of this study is to investigate the role of miR-324-3p on migration and invasion in NPC cells.