Primary pseudomyogenic haemangioendothelioma of bone: report of two cases

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• 作者：Alberto Righi (1)
  Marco Gambarotti (1)
  Piero Picci (1)
  Angelo Paolo Dei Tos (1) (2)
  Daniel Vanel (1)
  
  1. Pathology Department ; Rizzoli Institute ; Via del Barbiano 1/10 ; 40136 ; Bologna ; Italy
  2. Department of Pathology ; Treviso Regional Hospital ; Treviso ; Italy
  
• 关键词：Pseudomyogenic haemangioendothelioma ; Bone tumour ; Radius ; Multicentric ; Vascular neoplasm
• 刊名：Skeletal Radiology
• 出版年：2015
• 出版时间：May 2015
• 年：2015
• 卷：44
• 期：5
• 页码：727-731
• 全文大小：1,234 KB
• 参考文献：1. Billings, SD, Folpe, AL, Weiss, SW (2003) Epithelioid sarcoma-like hemangioendothelioma. Am J Surg Pathol 27: pp. 48-57 CrossRef
  2. Hornick, JL, Fletcher, CDM (2011) Pseudomyogenic hemangioendothelioma: a distinctive, often multicentric tumor with indolent behavior. Am J Surg Pathol 35: pp. 190-201 CrossRef
  3. Mirra, JM, Kessler, S, Bhuta, S (1992) The fibroma-like variant of epithelioid sarcoma: a fibrohistiocytic/myoid cell lesion often confused with benign and malignant spindle cell tumors. Cancer 9: pp. 1382-95 CrossRef
  4. Hornick, JL, Mertens, F, Fletcher, CDM Pseudomyogenic haemangioendothelioma. In: Fletcher, CDM, Bridge, JA, Hogendoorn, PCW, Mertens, F eds. (2013) World Health Organization Classification of Tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon, pp. 153-4
  5. Walther, C, Tayebwa, J, Lilljebj枚rn, H (2014) A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma. J Pathol 232: pp. 534-40 CrossRef
  6. Stuart, LN, Gardner, JM, Lauer, SR, Monson, DK, Parker, DC, Edgar, MA (2013) Epithelioid sarcoma-like (pseudomyogenic) hemangioendothelioma, clinically mimicking dermatofibroma, diagnosed by skin biopsy in a 30-year-old man. J Cutan Pathol 40: pp. 909-13
  7. Sheng, WQ, Wang, J (2012) Primary pseudomyogenic haemangioendothelioma of bone. Histopathology 61: pp. 1219-24 CrossRef
  8. McGinity, M, Bartanusz, V, Dengler, B, Birnbaum, L, Henry, J (2013) Pseudomyogenic hemangioendothelioma (epithelioid sarcoma-like hemangioendothelioma, fibroma-like variant of epithelioid sarcoma) of the thoracic spine. Eur Spine J 22: pp. S506-11 CrossRef
  9. Dei Tos, AP, Righi, A, Gambarotti, M (2014) Reappraisal of primary spindle/pleomorphic sarcomas of bone. Mod Pathol 27: pp. 15A
  10. Trombetta, D, Magnusson, L, Steyern, FV, Hornick, JL, Fletcher, CDM, Mertens, F (2011) Translocation t(7;19)(q22;q13)鈥攁 recurrent chromosome aberration in pseudomyogenic hemangioendothelioma?. Cancer Genet 204: pp. 211-5 CrossRef
  11. Evans, HL, Raymond, AK, Ayala, AG (2003) Vascular tumors of bone: a study of 17 cases other than ordinary hemangioma, with an evaluation of the relationship of hemangioendothelioma of bone to epithelioid hemangioma, epithelioid hemangioendothelioma, and high-grade angiosarcoma. Hum Pathol 34: pp. 680-9 CrossRef
  12. Nielsen, GP, Srivastava, A, Kattapuram, S (2009) Epithelioid hemangioma of bone revisited: a study of 50 cases. Am J Surg Pathol 33: pp. 270-7 CrossRef
  13. Kleer, CG, Unni, KK, McLeod, RA (1996) Epithelioid hemangioendothelioma of bone. Am J Surg Pathol 20: pp. 1301-11 CrossRef
  14. Deshpande, V, Rosenberg, AE, O鈥機onnell, JX, Nielsen, GP (2003) Epithelioid angiosarcoma of the bone: a series of 10 cases. Am J Surg Pathol 27: pp. 709-16 CrossRef
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Imaging and Radiology
  Orthopedics
  Pathology
  Nuclear Medicine
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-2161

文摘

Pseudomyogenic haemangioendothelioma (epithelioid sarcoma-like haemangioendothelioma) is a recently described, rarely metastasising neoplasm of the soft tissues that often presents as multiple discontinuous nodules in different tissue planes of a limb. This tumour type is extremely difficult to diagnose because no morphological evidence suggestive of endothelial differentiation is present to confirm a radiological suspicion of vascular neoplasm. All but one case published in the literature underline that bone involvement is secondary to deep and superficial soft tissue nodules. Here, we report two cases of primary bone pseudomyogenic haemangioendothelioma occurring in the radius and cuboid bone with a multifocal presentation.