Brain activation during processing of angry facial expressions in patients with alcohol dependency

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• 作者：Mi-Sook Park (1)
  Sook-Hee Kim (2)
  Sunju Sohn (3)
  Gap-Jung Kim (4)
  Yeon-Kyu Kim (5)
  Jin-Hun Sohn (1)
  
  1. Department of Psychology ; Chungnam National University ; 99 Daehak-ro ; Yuseong-gu ; Daejeon ; 305-764 ; South Korea
  2. Graduate School of Health and Complementary Medicine ; Wonkwang University ; 460 Iksandae-ro ; Iksan ; Jeonbuk ; 570-749 ; South Korea
  3. Department of Social Welfare ; Cheongju University ; 298 Daeseong-ro ; Cheongju-si ; Chungcheongbuk-do ; 363-764 ; South Korea
  4. Department of Psychiatry ; Hanmaum Alcohol Treatment Center ; 513-1 Jangan-dong ; Seo-gu ; Daejeon ; South Korea
  5. Department of Industrial Design ; Graduate school of Integrated Frontier Science ; Faculty of Design ; Kyushu University ; 4-9-1 Shiobaru ; Minami-ku ; Fukuoka ; 815-8540 ; Japan
  
• 关键词：Alcoholism ; Anger ; BOLD ; Anterior cingulate cortex ; Medial prefrontal cortex
• 刊名：Journal of Physiological Anthropology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：34
• 期：1
• 全文大小：1,044 KB
• 参考文献：1. Schonwetter, DJ, Janisse, MP (1991) Alcohol consumption, anger and hostility: a link to coronary heart disease. Pers Indiv Differ 12: pp. 1049-55 CrossRef
  2. Tivis, LJ, Parsons, OA, Nixon, SJ (1998) Anger in an inpatient treatment sample of chronic alcoholics. Alcohol Clin Exp Res 22: pp. 902-7 CrossRef
  3. McNair, DM, Lorr, M, Droppelman, LF (1971) Manual for the profile of mood states. San Diego, Educational and Industrial Testing Services
  4. Parrott, DJ, Zeichner, A, Stephens, D (2003) Effects of alcohol, personality, and provocation on the expression of anger in men: a facial coding analysis. Alcohol Clin Exp Res 27: pp. 937-45 CrossRef
  5. Kelly, JF, Magill, M, Stout, RL (2009) How do people recover from alcohol dependence? A systematic review of the research on mechanisms of behavior change in Alcoholics Anonymous. Addict Res Theory 17: pp. 236-59 CrossRef
  6. Handelsman, L, Stein, JA, Bernstein, DP, Oppenheim, SE, Rosenblum, A, Magura, S (2000) A latent variable analysis of coexisting emotional deficits in substance abusers: alexithymia, hostility, and PTSD. Addict Behav 25: pp. 423-8 CrossRef
  7. Salloum, JB, Ramchandani, VA, Bodurka, J, Rawlings, R, Momenan, R, George, D (2007) Blunted rostral anterior cingulate response during a simplified decoding task of negative emotional facial expressions in alcoholic patients. Alcohol Clin Exp Res 31: pp. 1490-504 CrossRef
  8. Lindquist, KA, Wager, TD, Kober, H, Bliss-Moreau, E, Barrett, LF (2012) The brain basis of emotion: a meta-analytic review. Behav Brain Sci 35: pp. 121-43 CrossRef
  9. Dougherty, DD, Shin, LM, Alpert, NM, Pitman, RK, Orr, SP, Lasko, M (1999) Anger in healthy men: a PET study using script-driven imagery. Biol Psychiatry 46: pp. 466-72 CrossRef
  10. Denson, TF, Pedersen, WC, Ronquillo, J, Nandy, AS (2009) The angry brain: neural correlates of anger, angry rumination, and aggressive personality. J Cogn Neurosci 21: pp. 734-44 CrossRef
  11. Kim, JS (1998) A understanding about recovery process of alcoholism. J Korean Acad Fam Med 19: pp. 304-12
  12. Park, BK, Kim, JS, Lee, DB (2000) Comparison of four alcoholism screening tools based on sensitivity and specificity for DSM-IV criteria. J Korean Acad Fam Med 21: pp. 1427-35
  13. Lee, DK, Shin, JK, Yun, SM, Byun, WT (2000) A reliability and validity study of the Korean Version of the Alcohol Dependence Scale in alcoholics. J Korean Acad Addict Psychiatry 4: pp. 30-7
  14. Lyons, MJ, Akamatsu, S, Kamachi, M, Gyoba, J (1998) Coding facial expressions with Gabor Wavelets. Third IEEE Proceedings of International Conference on Automatic Face and Gesture Recognition. IEEE Computer Society, Nara Japan
  15. Talairach, J, Tournoux, P (1988) Co-planar stereotaxic atlas of the human brain. George Thieme Verlag, New York
  16. Friston, KJ, Holmes, AP, Price, CJ, Buchel, C, Worsley, KJ (1999) Multisubject fMRI studies and conjunction analyses. Neuroimage 10: pp. 385-96 CrossRef
  17. Blair, RJR, Morris, JS, Frith, CD, Perrett, DI, Dolan, RJ (1999) Dissociable neural responses to facial expressions of sadness and anger. Brain 122: pp. 883-93 CrossRef
  18. Denson, TF, Dobson-Stone, C, Ronay, R, Hippel, W, Schira, MM (2014) A functional polymorphism of the MAOA gene is associated with neural responses to induced anger control. J Cogn Neurosci 26: pp. 1418-27 CrossRef
  19. Shenhav, A, Botvinick, MM, Cohen, JD (2013) The expected value of control: an integrative theory of anterior cingulate cortex function. Neuron 79: pp. 217-40 CrossRef
  20. Gasquoine, PG (2013) Localization of function in anterior cingulate cortex: from psychosurgery to functional neuroimaging. Neurosci and Biobehav R 37: pp. 340-8 CrossRef
  21. Eisenberger, NI, Lieberman, MD (2004) Why rejection hurts: a common neural alarm system for physical and social pain. Trends Cogn Sci 8: pp. 294-30 CrossRef
  22. Ochsner, KN (2008) The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond. Biol Psychiatry 64: pp. 48-61 CrossRef
  23. Philippot, P, Kornreich, C, Blairy, S, Baert, I, Dulk, A, Bon, O (1999) Alcoholics鈥?deficits in the decoding of emotional facial expression. Alcohol Clin Exp Res 23: pp. 1031-8
  24. Brower, KJ (2003) Insomnia, alcoholism and relapse. Sleep Med Rev 7: pp. 523-39 CrossRef
  25. Helm, E, Gujar, N, Walker, MP (2010) Sleep deprivation impairs the accurate recognition of human emotions. Sleep 33: pp. 335-42
  
• 刊物主题：Human Physiology; Anthropology;
• 出版者：BioMed Central
• ISSN：1880-6805

文摘

Background Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency. Methods Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls. Results During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC). Conclusions Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.