Kaoru Harada, for the Love of Amino Acids

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• 作者：Brack ; André
• 刊名：Origins of Life and Evolution of the Biosphere
• 出版年：2002
• 出版时间：2002
• 年：2002
• 卷：32
• 期：2
• 页码：83-90
• 全文大小：328 KB

文摘

The Yamato-791198 and Murchison carbonaceouschondrites were analyzed for dipeptides anddiketopiperazines as well as amino acids and hydantoins bygas chromatography combined with mass spectrometry. Glycylglycine (gly-gly) and cyclo(gly-gly) were detected atthe concentrations of 11 and 18 pmol g$^-1$, respectively,in Yamato-791198, and 4 and 23 pmol g$^-1$, respectively,in Murchison. No other dipeptide and diketopiperazine weredetected. Five hydantoins were detected at 8 to 65 pmolg$^-1$ in Yamato-791198 and seven in Murchison at 6 to 104pmol g$^-1$. Total concentration of the glycine (gly)dimers is approximately four orders of magnitude less thanthe concentration of free gly in Yamato-791198, and threeorders of magnitude less than that in Murchison. Theabsence of L- and LL-stereoisomers of dipeptides consistingof protein amino acids indicates that gly-gly andcyclo(gly-gly) detected are native to the chondrites and not fromterrestrial contaminants. A possibility was discussed thatthe gly dimers might have been formed by condensation of glymonomers but not formed through N-carboxyanhydrides of gly.