Les adipokines : état des lieux et nouveautés

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• 作者：J.-P. Bastard ; C. Bastard ; S. Fellahi ; C. Vatier ; J. Capeau ; B. Fève
• 关键词：Mots clésObésité ; Adipokine ; Tissu adipeux
• 刊名：Ob¨¦sit¨¦
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：11
• 期：3
• 页码：181-193
• 全文大小：244 KB
• 刊物主题：Medicine/Public Health, general; Public Health; Endocrinology; Metabolic Diseases; Quality of Life Research; Diabetes;
• 出版者：Springer Paris
• ISSN：1951-6002
• 卷排序：11

文摘

Adipose tissue is now recognized as an endocrine organ able to synthesize and secrete several hundred molecules molecules, which exert pleiotropic actions in particular on the regulation of carbohydrate and lipid metabolism, inflammation, angiogenesis, or reproduction. These molecules are gathered under the term adipokines. Many studies have been done on “leading” adipokines, leptin, and adiponectin, particularly because of their involvement in energy metabolism. However, many other adipokines have been more recently identified and represent promising targets in the context of metabolic disorders associated with obesity. In this review, we present a non-exhaustive point of “classic” and more recently discovered adipokines in the field of obesity and metabolic diseases.