Patient-reported outcomes (PRO) focused on adverse events (PRO-AEs) in adjuvant and metastatic breast cancer: clinical and translational implications

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• 作者：Stefan Stefanovic ; Markus Wallwiener ; Uros Karic…
• 关键词：Patient ; reported outcome ; Adverse events ; Breast cancer ; Adjuvant ; Metastatic
• 刊名：Supportive Care in Cancer
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：25
• 期：2
• 页码：549-558
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology; Nursing; Nursing Research; Pain Medicine; Rehabilitation Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1433-7339
• 卷排序：25

文摘

PurposeThe capture of adequate treatment outcomes and quality of life (QOL) of advanced breast cancer patients in clinical routine represents a great challenge. Patient-reported outcomes (PROs) are data elements directly reported by patients about experiences with care, including symptoms, functional status, or quality of life. There is growing interest in the medical community for the evaluation and implementation of PROs of adverse events (PRO-AEs). Recent interest in PROs in health care has evolved in the context of patient centeredness. Our primary objective was to identify trials that had implemented PRO-AEs in the breast cancer treatment setting, thereby demonstrating its feasibility. We aimed to identify published studies that used patient reports to assess AEs during and after breast cancer treatment, to identify clinician underreported and modifiable AEs that are important to patients, and to analyze the feasibility and usefulness of PRO instrument implementation in everyday oncological practice with special attention given to electronic-based PRO instruments.