Nuclear myocardial perfusion imaging with a novel cadmium-zinc-telluride detector SPECT/CT device: first validation versus invasive coronary angiography

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• 作者：Michael Fiechter (12)
  Jelena R. Ghadri (1)
  Silke M. Kuest (1)
  Aju P. Pazhenkottil (1)
  Mathias Wolfrum (1)
  Rene N. Nkoulou (1)
  Robert Goetti (1)
  Oliver Gaemperli (1)
  Philipp A. Kaufmann (12) pak@usz.ch
• 关键词：CZT &#8211 ; SPECT &#8211 ; MPI &#8211 ; Invasive coronary angiography &#8211 ; Accuracy &#8211 ; Attenuation correction
• 刊名：European Journal of Nuclear Medicine and Molecular Imaging
• 出版年：2011
• 出版时间：November 2011
• 年：2011
• 卷：38
• 期：11
• 页码：2025-2030
• 全文大小：177.1 KB
• 参考文献：1. Madsen MT. Recent advances in SPECT imaging. J Nucl Med 2007;48:661–73.
  2. Sharir T, Ben-Haim S, Merzon K, Prochorov V, Dickman D, Ben-Haim S, et al. High-speed myocardial perfusion imaging initial clinical comparison with conventional dual detector anger camera imaging. JACC Cardiovasc Imaging 2008;1:156–63.
  3. Herzog BA, Buechel RR, Husmann L, Pazhenkottil AP, Burger IA, Wolfrum M, et al. Validation of CT attenuation correction for high-speed myocardial perfusion imaging using a novel cadmium-zinc-telluride detector technique. J Nucl Med 2010;51:1539–44.
  4. Buechel RR, Herzog BA, Husmann L, Burger IA, Pazhenkottil AP, Treyer V, et al. Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation. Eur J Nucl Med Mol Imaging 2010;37:773–8.
  5. Pazhenkottil AP, Buechel RR, Herzog BA, Nkoulou RN, Valenta I, Fehlmann U, et al. Ultrafast assessment of left ventricular dyssynchrony from nuclear myocardial perfusion imaging on a new high-speed gamma camera. Eur J Nucl Med Mol Imaging 2010;37:2086–92.
  6. Herzog BA, Buechel RR, Katz R, Brueckner M, Husmann L, Burger IA, et al. Nuclear myocardial perfusion imaging with a cadmium-zinc-telluride detector technique: optimized protocol for scan time reduction. J Nucl Med 2009;51:46–51.
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  9. Berman DS, Kiat H, Friedman JD, Wang FP, van Train K, Matzer L, et al. Separate acquisition rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion single-photon emission computed tomography: a clinical validation study. J Am Coll Cardiol 1993;22:1455–64.
  10. Pazhenkottil AP, Nkoulou RN, Ghadri JR, Herzog BA, Buechel RR, K眉est SM, et al. Prognostic value of cardiac hybrid imaging integrating single-photon emission computed tomography with coronary computed tomography angiography. Eur Heart J 2011;32:1465–71. doi:
  11. Gaemperli O, Husmann L, Schepis T, Koepfli P, Valenta I, Jenni W, et al. Coronary CT angiography and myocardial perfusion imaging to detect flow-limiting stenoses: a potential gatekeeper for coronary revascularization? Eur Heart J 2009;30:2921–9.
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  16. Gaemperli O, Kaufmann PA. Multimodality cardiac imaging. J Nucl Cardiol 2010;17:4–7.
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  18. Pazhenkottil AP, Ghadri JR, Nkoulou RN, Wolfrum M, Buechel RR, K眉est SM, et al. Improved outcome prediction by SPECT myocardial perfusion imaging after CT attenuation correction. J Nucl Med 2011;52:196–200.
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  20. Nkoulou RN PA, Kuest SM, Ghadri JR, Wolfrum M, Husmann L, Fiechter M, Buechel RR, Herzog BA, Koepfli P, Burger C, Gaemperli O, Kaufmann PA. Semiconductor detectors allow low-dose/low-dose one-day SPECT myocardial perfusion imaging. J Nucl Med 2011; in press.
  21. Buechel RR, Pazhenkottil AP, Herzog BA, Husmann L, Nkoulou RN, Burger IA, et al. Real-time breath-hold triggering of myocardial perfusion imaging with a novel cadmium-zinc-telluride detector gamma camera. Eur J Nucl Med Mol Imaging 2010;37:1903–8.
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• 作者单位：1. Department of Radiology, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland2. Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Nuclear Medicine
  Imaging and Radiology
  Orthopedics
  Cardiology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1619-7089

文摘

Purpose We evaluated the diagnostic accuracy of attenuation corrected nuclear myocardial perfusion imaging (MPI) with a novel hybrid single photon emission computed tomography (SPECT)/CT device consisting of an ultrafast dedicated cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors integrated onto a multislice CT scanner to detect coronary artery disease (CAD). Invasive coronary angiography served as the standard of reference.