Diagnostic and therapeutic advancements for aerobic vaginitis

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• 作者：Cha Han (1)
  Wenjuan Wu (1)
  Aiping Fan (1)
  Yingmei Wang (1)
  Huiying Zhang (1)
  Zanjun Chu (1)
  Chen Wang (1)
  Fengxia Xue (1)
  
  1. Department of Gynecology and Obstetrics ; Tianjin Medical University General Hospital ; No. 154 Anshan Road ; Heping District ; Tianjin ; 300052 ; People鈥檚 Republic of China
  
• 关键词：Vaginal flora ; Aerobic vaginitis ; Bacterial vaginosis ; Pregnancy
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：291
• 期：2
• 页码：251-257
• 全文大小：210 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Gynecology
  Obstetrics and Perinatology
  Endocrinology
  Human Genetics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0711

文摘

Background Aerobic vaginitis (AV) is a newly defined clinical entity that is distinct from candidiasis, trichomoniasis and bacterial vaginosis (BV). Because of the poor recognition of AV, this condition can lead to treatment failures and is associated with severe complications, such as pelvic inflammatory disease, infertility, preterm birth and foetal infections. Objective This review describes the diagnosis and treatment of AV and the relationship between AV and pregnancy. Results The characteristics of AV include severely depressed levels of lactobacilli, increased levels of aerobic bacteria and an inflamed vagina. The diagnosis is made by microscopy on wet mounts of fresh vaginal fluid, and some distinct clinical features are recognized. Vaginal suppositories that contain kanamycin or clindamycin have shown curative effects in nonpregnant women. Additionally, the application of topical probiotics can restore the vaginal flora and reduce the recurrence of AV. Clindamycin vaginal suppositories and probiotics may be a better choice for gravida with AV than metronidazole. AV requires prompt attention, and the early diagnosis and treatment of AV during pregnancy significantly improves perinatal outcomes. Conclusion Further research is needed to define the pathogenesis, diagnostic criteria and standard treatment guidelines for AV.