Inhibition of pancreatic cancer cell migration by plasma anthocyanins isolated from healthy volunteers receiving an anthocyanin-rich berry juice

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• 作者：Sabine Kuntz ; Clemens Kunz ; Silvia Rudloff
• 关键词：Grapes and bilberries ; Anthocyanins ; Pancreatic cancer cells ; Metalloproteinases ; Migration
• 刊名：European Journal of Nutrition
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：56
• 期：1
• 页码：203-214
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Nutrition;
• 出版者：Springer Berlin Heidelberg
• ISSN：1435-1293
• 卷排序：56

文摘

PurposePancreatic cancer is an aggressive cancer type, of which the most important characteristics are migration and metastasis. Anthocyanins (ACN) are discussed to be protective phytochemicals; however, up to now only scarce data are available regarding their effects on cancer prevention. In this study, we aimed to determine whether ACN and their metabolites from plasma (PAM), isolated from blood of healthy volunteers after ingestion of an ACN-rich juice, are effective in modulating cancer cell migration in vitro.