A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients
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- 作者：Agnieszka Paziewska ; Andrzej Habior ; Agnieszka Rogowska…
- 关键词：Genome ; wide association study ; Primary biliary cholangitis ; Primary sclerosing cholangitis
- 刊名：BMC Medical Genomics
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：381KB
- 刊物主题：Human Genetics; Microarrays; Gene Expression;
- 出版者：BioMed Central
- ISSN：1755-8794
- 卷排序：10
文摘
BackgroundPrimary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are forms of hepatic autoimmunity, and risk for both diseases has a strong genetic component. This study aimed to define the genetic architecture of PBC and PSC within the Polish population.