A review of economic evaluation models for cardiac resynchronization therapy with implantable cardioverter defibrillators in patients with heart failure

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• 作者：F. Tomini ; F. Prinzen ; A. D. I. van Asselt
• 关键词：Review ; Cost ; effectiveness ; Cardiac resynchronization therapy ; Cardiac pacing ; Implantable cardioverter ; defibrillator ; Markov chains ; Models ; Economic ; Heart failure ; Sudden cardiac death
• 刊名：The European Journal of Health Economics
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：9
• 页码：1159-1172
• 全文大小：575 KB
• 刊物类别：Business and Economics
• 刊物主题：Economics
  Economic Policy
  Public Health
  Public Finance and Economics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1618-7601
• 卷排序：17

文摘

ObjectivesCardiac resynchronization therapy with a biventricular pacemaker (CRT-P) is an effective treatment for dyssynchronous heart failure (DHF). Adding an implantable cardioverter defibrillator (CRT-D) may further reduce the risk of sudden cardiac death (SCD). However, if the majority of patients do not require shock therapy, the cost-effectiveness ratio of CRT-D compared to CRT-P may be high. The objective of this study was to systematically review decision models evaluating the cost-effectiveness of CRT-D for patients with DHF, compare the structure and inputs of these models and identify the main factors influencing the ICERs for CRT-D.