Infective endocarditis following tumor necrosis factor-α antagonist therapy for management of psoriatic erythroderma: a case report
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- 作者：Takuro Mizuno ; Jun Kiyosawa ; Akihiro Fukuda…
- 关键词：TNF ; α antagonist ; Psoriasis erythroderma ; Bacterial endocarditis
- 刊名：Journal of Medical Case Reports
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：11
- 期：1
- 全文大小：1060KB
- 刊物主题：Medicine/Public Health, general; General Practice / Family Medicine; Public Health; Primary Care Medicine;
- 出版者：BioMed Central
- ISSN：1752-1947
- 卷排序：11
文摘
BackgroundThe introduction of biological agents, such as infliximab, which act against tumor necrosis factor-α was a major advance for the treatment of an increasing number of chronic diseases. Tumor necrosis factor-α antagonists represent a major therapeutic advance for the management of chronic inflammatory diseases, such as psoriasis. Previous studies have reported that the use of tumor necrosis factor-α antagonists increased the risk of opportunistic infections and reactivation of latent bacterial infections. Cardiac involvement, such as infective endocarditis, is very rare in the literature.