文摘
Specific patterns of cerebral activation during the performance of various tasks and the presentation of various visual or tactile stimuli can be shown with functional magnetic resonance imaging (fMRI). Using more recent methods, such as resting state fMRI, spontaneous brain activity can be measured, which can also show specific alterations in different groups and different activation patterns have been shown for specific subgroups, specifically for men and women. It was initially assumed that transsexual persons showed patterns which lie inbetween the typical patternsaditional gender groups (i.e. men and women); however, a more differentiated interpretation of the results of studies is needed and show contradictory results with respect to the nature of the presented stimuli. The influence of hormone replacement therapy on cognitive abilities and correlates in cerebral activity patterns is also controversially discussed. The results of imaging studies in transsexual persons can provide fascinating insights into the interaction between biological, social, cultural, cognitive and sexual components but also show the limitations of the method.