Artificial Bone via Bone Tissue Engineering: Current Scenario and Challenges
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- 作者：Shivaji Kashte ; Amit Kumar Jaiswal…
- 关键词：Bone ; Bone tissue engineering ; Scaffolds ; Growth factors ; Regenerative medicine
- 刊名：Tissue Engineering and Regenerative Medicine
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：14
- 期：1
- 页码：1-14
- 全文大小：
- 刊物主题：Regenerative Medicine/Tissue Engineering; Biomedical Engineering; Stem Cells; Cell Biology;
- 出版者：Korean Tissue Engineering and Regenerative Medicine Society
- ISSN：2212-5469
- 卷排序：14
文摘
Bone provides mechanical support, and flexibility to the body as a structural frame work along with mineral storage, homeostasis, and blood pH regulation. The repair and/or replacement of injured or defective bone with healthy bone or bone substitute is a critical problem in orthopedic treatment. Recent advances in tissue engineering have shown promising results in developing bone material capable of substituting the conventional autogenic or allogenic bone transplants. In the present review, we have discussed natural and synthetic scaffold materials such as metal and metal alloys, ceramics, polymers, etc. which are widely being used along with their cellular counterparts such as stem cells in bone tissue engineering with their pros and cons.