用户名： 密码： 验证码：
Brachytherapy in Gynecologic Cancers: Why Is It Underused?
详细信息    查看全文
  • 作者：Kathy Han ; Akila N. Viswanathan
  • 关键词：Brachytherapy ; Gynecologic cancer ; Cervical cancer ; Vaginal cancer ; Utilization ; Intensity ; modulated radiotherapy
  • 刊名：Current Oncology Reports
  • 出版年：2016
  • 出版时间：April 2016
  • 年：2016
  • 卷：18
  • 期：4
  • 全文大小：253 KB
  • 参考文献：1.Georg D, Kirisits C, Hillbrand M, Dimopoulos J, Potter R. Image-guided radiotherapy for cervix cancer: high-tech external beam therapy versus high-tech brachytherapy. Int J Radiat Oncol Biol Phys. 2008;71(4):1272–8.CrossRef PubMed
    2.Patel MK, Cote ML, Ali-Fehmi R, Buekers T, Munkarah AR, Elshaikh MA. Trends in the utilization of adjuvant vaginal cuff brachytherapy and/or external beam radiation treatment in stage I and II endometrial cancer: a surveillance, epidemiology, and end-results study. Int J Radiat Oncol Biol Phys. 2012;83(1):178–84.CrossRef PubMed
    3.Nout RA, Smit VT, Putter H, Jurgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial. Lancet. 2010;375(9717):816–23.CrossRef PubMed
    4.Montana GS, Fowler WC, Varia MA, Walton LA, Mack Y, Shemanski L. Carcinoma of the cervix, stage III. Results of radiation therapy. Cancer. 1986;57(1):148–54.CrossRef PubMed
    5.Lanciano RM, Martz K, Coia LR, Hanks GE. Tumor and treatment factors improving outcome in stage III-B cervix cancer. Int J Radiat Oncol Biol Phys. 1991;20(1):95–100.CrossRef PubMed
    6.Hanks GE, Herring DF, Kramer S. Patterns of care outcome studies. Results of the national practice in cancer of the cervix. Cancer. 1983;51(5):959–67.CrossRef PubMed
    7.Corn BW, Hanlon AL, Pajak TF, Owen J, Hanks GE. Technically accurate intracavitary insertions improve pelvic control and survival among patients with locally advanced carcinoma of the uterine cervix. Gynecol Oncol. 1994;53(3):294–300.CrossRef PubMed
    8.Viswanathan AN, Moughan J, Small Jr W, Levenback C, Iyer R, Hymes S, et al. The quality of cervical cancer brachytherapy implantation and the impact on local recurrence and disease-free survival in radiation therapy oncology group prospective trials 0116 and 0128. Int J Gynecol Cancer. 2012;22(1):123–31.CrossRef PubMed PubMedCentral
    9.Erickson B, Eifel P, Moughan J, Rownd J, Iarocci T, Owen J. Patterns of brachytherapy practice for patients with carcinoma of the cervix (1996–1999): a patterns of care study. Int J Radiat Oncol Biol Phys. 2005;63(4):1083–92.CrossRef PubMed
    10.••
Eifel PJ, Ho A, Khalid N, Erickson B, Owen J. Patterns of radiation therapy practice for patients treated for intact cervical cancer in 2005 to 2007: a quality research in radiation oncology study. Int J Radiat Oncol Biol Phys. 2014;89(2):249–56. This most recent QRRO (formerly Patterns of Care) study showed that the proportion of patients with cervical cancer that did not receive brachytherapy as part of their treatment in 2005–2007 was double than that reported in the 1996–1999 survey, and that patients treated in non-academic centers were less likely to receive brachytherapy.CrossRef PubMed
11.••
Han K, Milosevic M, Fyles A, Pintilie M, Viswanathan AN. Trends in the utilization of brachytherapy in cervical cancer in the United States. Int J Radiat Oncol Biol Phys. 2013;87(1):111–9. This was the first population-based study to show a concerning decline in brachytherapy utilization in cervical cancer using the SEER database.CrossRef PubMed
12.••
Gill BS, Lin JF, Krivak TC, Sukumvanich P, Laskey RA, Ross MS, et al. National cancer data base analysis of radiation therapy consolidation modality for cervical cancer: the impact of new technological advancements. Int J Radiat Oncol Biol Phys. 2014;90(5):1083–90. This population-based study also showed a decline in brachytherapy utilization in cervical cancer and a corresponding increase in IMRT/SBRT use.CrossRef PubMed
13.Smith GL, Jiang J, Giordano SH, Meyer LA, Eifel PJ. Trends in the quality of treatment for patients with intact cervical cancer in the United States, 1999 through 2011. Int J Radiat Oncol Biol Phys. 2015;92(2):260–7.CrossRef PubMed
14.Tomita N, Toita T, Kodaira T, Shinoda A, Uno T, Numasaki H, et al. Patterns of radiotherapy practice for patients with cervical cancer in Japan, 2003–2005: changing trends in the pattern of care process. Int J Radiat Oncol Biol Phys. 2012;83(5):1506–13.CrossRef PubMed
15.Capelle L, Stevens W, Brooks S. Patterns of care for cervical cancer in Auckland, New Zealand, 2003–2007. J Med Imaging Radiat Oncol. 2011;55(1):82–9.CrossRef PubMed
16.Abdel-Wahab M, Bourque JM, Pynda Y, Izewska J, Van der Merwe D, Zubizarreta E, et al. Status of radiotherapy resources in Africa: an International Atomic Energy Agency analysis. Lancet Oncol. 2013;14(4):e168–75.CrossRef PubMed
17.Maranga IO, Hampson L, Oliver AW, Gamal A, Gichangi P, Opiyo A, et al. Analysis of factors contributing to the low survival of cervical cancer patients undergoing radiotherapy in Kenya. PLoS One. 2013;8(10), e78411.CrossRef PubMed PubMedCentral
18.Rosenblatt E, Zubizarreta E, Izewska J, Binia S, Garcia-Yip F, Jimenez P. Quality audits of radiotherapy centres in Latin America: a pilot experience of the International Atomic Energy Agency. Radiat Oncol. 2015;10:169.CrossRef PubMed PubMedCentral
19.Petereit DG, Frank SJ, Viswanathan AN, Erickson B, Eifel P, Nguyen PL, et al. Brachytherapy: where has it gone? J Clin Oncol. 2015;33(9):980–2.CrossRef PubMed
20.Compton JJ, Gaspar LE, Shrieve DC, Wilson LD, Griem KL, Amdur RJ, et al. Resident-reported brachytherapy experience in ACGME-accredited radiation oncology training programs. Brachytherapy. 2013;12(6):622–7.CrossRef PubMed
21.Beriwal S, Demanes DJ, Erickson B, Jones E, De Los Santos JF, Cormack RA, et al. American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer. Brachytherapy. 2012;11(1):68–75.CrossRef PubMed
22.Chyle V, Zagars GK, Wheeler JA, Wharton JT, Delclos L. Definitive radiotherapy for carcinoma of the vagina: outcome and prognostic factors. Int J Radiat Oncol Biol Phys. 1996;35(5):891–905.CrossRef PubMed
23.Frank SJ, Jhingran A, Levenback C, Eifel PJ. Definitive radiation therapy for squamous cell carcinoma of the vagina. Int J Radiat Oncol Biol Phys. 2005;62(1):138–47.CrossRef PubMed
24.Kushner DM, Fleming PA, Kennedy AW, Wilkinson DA, Lee E, Saffle PA. High dose rate (192)Ir afterloading brachytherapy for cancer of the vagina. Br J Radiol. 2003;76(910):719–25.CrossRef PubMed
25.Nori D, Hilaris BS, Stanimir G, Lewis Jr JL. Radiation therapy of primary vaginal carcinoma. Int J Radiat Oncol Biol Phys. 1983;9(10):1471–5.CrossRef PubMed
26.de Crevoisier R, Sanfilippo N, Gerbaulet A, Morice P, Pomel C, Castaigne D, et al. Exclusive radiotherapy for primary squamous cell carcinoma of the vagina. Radiother Oncol. 2007;85(3):362–70.CrossRef PubMed
27.Thompson SR, Delaney GP, Gabriel GS, Jacob S, Barton MB. Estimation of the optimal brachytherapy utilisation rate in the treatment of vaginal cancer and comparison with patterns of care. J Med Imaging Radiat Oncol. 2012;56(4):483–9.CrossRef PubMed
28.Ghia AJ, Gonzalez VJ, Tward JD, Stroup AM, Pappas L, Gaffney DK. Primary vaginal cancer and chemoradiotherapy: a patterns-of-care analysis. Int J Gynecol Cancer. 2011;21(2):378–84.CrossRef PubMed
29.••
Rajagopalan MS, Xu KM, Lin J, Hansen K, Sukumvanich P, Krivak TC, et al. Patterns of care and brachytherapy boost utilization for vaginal cancer in the United States. Pract Radiat Oncol. 2015;5(1):56–61. This NCDB study showed a concerning decline in brachytherapy utilization rate in vaginal cancer between 2004 and 2011, and a corresponding increase in nonbrachytherapy modalities.CrossRef PubMed
30.Wallner PE, Kupelian P, Erickson B, Alektiar KM, Laszakovits D, Henson TM, et al. The American Board of Radiology Focused Practice Recognition in Brachytherapy (FPRB) Program: opportunities lost, lessons learned, and future implications. Pract Radiat Oncol. 2015;5(6):427–32.CrossRef PubMed
31.Atun R, Jaffray DA, Barton MB, Bray F, Baumann M, Vikram B, et al. Expanding global access to radiotherapy. Lancet Oncol. 2015;16(10):1153–86.CrossRef PubMed
32.Implementation of high dose rate brachytherapy in limited resource settings. IAEA human health series No 30. Vienna: International Atomic Energy Agency; 2015. http://​www-pub.​iaea.​org/​MTCD/​Publications/​PDF/​Pub1670web- 5444797.​pdf .
33.Einck JP, Hudson A, Shulman AC, Yashar CM, Dieng MM, Diagne M, et al. Implementation of a high-dose-rate brachytherapy program for carcinoma of the cervix in Senegal: a pragmatic model for the developing world. Int J Radiat Oncol Biol Phys. 2014;89(3):462–7.CrossRef PubMed
34.Efstathiou JA, Bvochora-Nsingo M, Gierga DP, Alphonse Kayembe MK, Mmalane M, Russell AH, et al. Addressing the growing cancer burden in the wake of the AIDS epidemic in Botswana: the BOTSOGO collaborative partnership. Int J Radiat Oncol Biol Phys. 2014;89(3):468–75.CrossRef PubMed
  • 作者单位：Kathy Han (1)
    Akila N. Viswanathan (2)

    1. Department of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
    2. Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women’s Hospital, 75 Francis Street, ASB1-L2, Boston, MA, 02115, USA
  • 刊物主题：Oncology;
  • 出版者：Springer US
  • ISSN：1534-6269
    • 文摘
    Despite its established efficacy, brachytherapy is underused in the management of cervical and vaginal cancers in some parts of the world. Possible reasons for the underutilization of brachytherapy include the adoption of less invasive techniques, such as intensity-modulated radiotherapy; reimbursement policies favoring these techniques over brachytherapy; poor physician or patient access to brachytherapy; inadequate maintenance of brachytherapy skills among practicing radiation oncologists; transitioning to high-dose-rate (HDR) brachytherapy with increased time requirements; and insufficient training of radiation oncology residents.

    © 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

    地址：北京市海淀区学院路29号 邮编：100083

    电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700